Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which works by mimicking the effects of a natural hormone called GLP-1 in the body. The medication is administered through a subcutaneous injection once a week, and it works by reducing appetite, increasing feelings of fullness, and slowing down the digestion rate of food to reduce calorie intake and promote weight loss. Clinical trials have shown significant weight loss in patients treated with Semaglutide compared to those treated with a placebo. Semaglutide has also been proven to help improve glycemic control and blood pressure in patients with type 2 diabetes, and it may have a positive impact on other obesity-related comorbidities such as sleep apnea and nonalcoholic fatty liver disease.
As with any medication, there are potential side effects associated with the use of Semaglutide, including nausea, diarrhea, vomiting, and constipation. More serious side effects may include pancreatitis, gallbladder disease, and kidney problems. Patients considering Semaglutide for weight loss should discuss the potential risks and benefits with their healthcare provider to determine if this medication is an appropriate treatment option for them.